期刊
CHEMICAL COMMUNICATIONS
卷 -, 期 23, 页码 2843-2846出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/b311008g
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The oxidation of polyunsaturated fatty acids such as arachidonic and linoleic acid initiates a plethora of cell signaling pathways in animals and plants. The chemistry of the enzymatic oxidation has been investigated for several enzymes, most notably prostaglandin synthase and the lipoxygenases, revealing many surprises and impressive examples of enzymatic control of hydrogen atom abstraction and subsequent oxygenation.
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