期刊
CELL COMMUNICATION AND ADHESION
卷 15, 期 4, 页码 379-383出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/15419060802440054
关键词
Cre; loxP; FAK; fibronectin; MEF; p53
资金
- American Heart Association Established Investigator [0540115N]
- National Institutes of Health [CA102310]
- [CA87652]
- NATIONAL CANCER INSTITUTE [R01CA102310, K01CA087652] Funding Source: NIH RePORTER
It is often difficult to determine molecular mechanisms leading to early embryonic lethality of genetically modified mice due to lack of cells for further analyses. The authors describe here establishment of mouse embryonic fibroblast (MEF) cell lines from gastrulation stage embryos. In this example, using a combination of in vivo and in vitro techniques, the authors successfully generated MEF cell lines that lack both fibronectin (FN) and focal adhesion kinase (FAK).
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据