期刊
CLINICAL INFECTIOUS DISEASES
卷 37, 期 9, 页码 E129-E131出版社
OXFORD UNIV PRESS INC
DOI: 10.1086/378891
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West Nile virus (WNV) can cause severe, potentially fatal neurological illnesses, which include encephalitis, meningitis, Guillain-Barre syndrome, and anterior myelitis. Because of the short viremic phase, WNV infection is most commonly diagnosed by detection of immunoglobulin M antibody to WNV in serum or cerebrospinal fluid (CSF). We describe a patient with T cell lymphoma who had undergone a T cell depleted bone marrow transplantation and developed fatal WNV infection. The results of serological tests of blood samples and of CSF tests were negative. Diagnosis was made postmortem by a positive result of reverse-transcriptase-polymerase chain reaction (ABI 7700; TaqMan) for WNV in stored CSF and serum samples.
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