Synthesis of 11H-pyrido[2,1-b]quinazolin-11-one and derivatives using ultrasound irradiation

An improved synthesis of 11H-pyrido[2,1-b]quinazolin-11-one and derivatives, by the condensation of 2-chlorobenzoic acid and 2-aminopyridine derivatives in N,N-dimethylformamide (DMF) is reported using ultrasound irradiation. The derivatives were prepared in good yield and in a short reaction time.