期刊
NATURE MEDICINE
卷 9, 期 1, 页码 118-122出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nm0103-118
关键词
-
资金
- NCI [PO1 CA78040]
- NIDA [RO1 DA09410]
- MSNRI
- NATIONAL CANCER INSTITUTE [P01CA078040] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON DRUG ABUSE [R01DA009410] Funding Source: NIH RePORTER
The conceptual and technical approaches that led to the explosive growth of combinatorial chemistry began approximately 20 years ago. In the past decade, combinatorial chemistry has continued to expand with new chemistries, technological improvements and, most importantly, a clear demonstration of its utility in the identification of active compounds for research and drug-discovery programs. This article describes the conceptual and practical breakthroughs that have been critical for the development of synthetic combinatorial methods and includes the most recent developments and applications of mixture-based combinatorial libraries.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据