相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Myocardial deletion of Smad4 using a novel α skeletal muscle actin Cre recombinase transgenic mouse causes misalignment of the cardiac outflow tract
Mohamad Azhar et al.
International Journal of Biological Sciences (2012)
SMAD4 Mutation Segregating in a Family With Juvenile Polyposis, Aortopathy, and Mitral Valve Dysfunction
Sara Andrabi et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2011)
Inhibition of Transforming Growth Factor β Worsens Elastin Degradation in a Murine Model of Kawasaki Disease
Cristina M. Alvira et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Heart Valve Structure and Function in Development and Disease
Robert B. Hinton et al.
ANNUAL REVIEW OF PHYSIOLOGY, VOL 73 (2011)
BMP Signaling in Congenital Heart Disease: New Developments and Future Directions
Jun Wang et al.
BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY (2011)
Transcriptional regulation of heart valve development and disease
Elaine E. Wirrig et al.
CARDIOVASCULAR PATHOLOGY (2011)
Angiotensin II increases periostin expression via Ras/p38 MAPK/CREB and ERK1/2/TGF-β1 pathways in cardiac fibroblasts
Li Li et al.
CARDIOVASCULAR RESEARCH (2011)
Heart Disease and Stroke Statistics-2011 Update A Report From the American Heart Association
Veronique L. Roger et al.
CIRCULATION (2011)
Transforming Growth Factor-β Signaling Pathway in Patients With Kawasaki Disease
Chisato Shimizu et al.
CIRCULATION-CARDIOVASCULAR GENETICS (2011)
Combined cardiological and neurological abnormalities due to filamin A gene mutation
Marie Claire Y. de Wit et al.
CLINICAL RESEARCH IN CARDIOLOGY (2011)
Cell Autonomous Requirement of Endocardial Smad4 During Atrioventricular Cushion Development in Mouse Embryos
Langying Song et al.
DEVELOPMENTAL DYNAMICS (2011)
Long Form of Latent TGF-beta Binding Protein 1 (Ltbp1L) Regulates Cardiac Valve Development
Vesna Todorovic et al.
DEVELOPMENTAL DYNAMICS (2011)
Lessons on the pathogenesis of aneurysm from heritable conditions
Mark E. Lindsay et al.
NATURE (2011)
Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis
Ingrid M. B. H. van de laar et al.
NATURE GENETICS (2011)
Cardiac-specific transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development
Ivan P. Moskowitz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Repeated Daclizumab Administration to Delay the Introduction of Calcineurin Inhibitors in Heart Transplant Patients With Postoperative Renal Dysfunction
Ignacio J. Sanchez Lazaro et al.
REVISTA ESPANOLA DE CARDIOLOGIA (2011)
Noncanonical TGFβ Signaling Contributes to Aortic Aneurysm Progression in Marfan Syndrome Mice
Tammy M. Holm et al.
SCIENCE (2011)
Angiotensin II Type 2 Receptor Signaling Attenuates Aortic Aneurysm in Mice Through ERK Antagonism
Jennifer P. Habashi et al.
SCIENCE (2011)
Extracellular signal-regulated kinase 1/2 (ERK1/2) signaling in cardiac hypertrophy
Izhak Kehat et al.
ANALYSIS OF CARDIAC DEVELOPMENT: FROM EMBRYO TO OLD AGE (2010)
Developmental basis of adult cardiovascular diseases Valvular heart diseases
Roger R. Markwald et al.
ANALYSIS OF CARDIAC DEVELOPMENT: FROM EMBRYO TO OLD AGE (2010)
Selective Visualization of Cyclooxygenase-2 in Inflammation and Cancer by Targeted Fluorescent Imaging Agents
Md. Jashim Uddin et al.
CANCER RESEARCH (2010)
Common pathogenic features of atherosclerosis and calcific aortic stenosis: role of transforming growth factor-β
Songyi Xu et al.
CARDIOVASCULAR PATHOLOGY (2010)
Research Priorities in Hypertrophic Cardiomyopathy Report of a Working Group of the National Heart, Lung, and Blood Institute
Thomas Force et al.
CIRCULATION (2010)
Elastin Haploinsufficiency Results in Progressive Aortic Valve Malformation and Latent Valve Disease in a Mouse Model
Robert B. Hinton et al.
CIRCULATION RESEARCH (2010)
The association between transforming growth factor β3 polymorphisms and left ventricular structure in hypertensive subjects
Bang-Chuan Hu et al.
CLINICA CHIMICA ACTA (2010)
Expression of the Familial Cardiac Valvular Dystrophy Gene, Filamin-A, During Heart Morphogenesis
R. A. Norris et al.
DEVELOPMENTAL DYNAMICS (2010)
The TGFβ Type II Receptor Plays a Critical Role in the Endothelial Cells During Cardiac Development
Andrew Robson et al.
DEVELOPMENTAL DYNAMICS (2010)
Blockade of Endothelial-Mesenchymal Transition by a Smad3 Inhibitor Delays the Early Development of Streptozotocin-Induced Diabetic Nephropathy
Jinhua Li et al.
DIABETES (2010)
Bone morphogenetic protein receptors and signal transduction
Kohei Miyazono et al.
JOURNAL OF BIOCHEMISTRY (2010)
Cellular and molecular basis for the regulation of inflammation by TGF-beta
Akihiko Yoshimura et al.
JOURNAL OF BIOCHEMISTRY (2010)
Quantitative analysis of TGFBR2 mutations in Marfan-syndrome-related disorders suggests a correlation between phenotypic severity and Smad signaling activity
Daniel Horbelt et al.
JOURNAL OF CELL SCIENCE (2010)
TGF-β in the pathogenesis and prevention of disease: a matter of aneurysmic proportions
Harry C. Dietz
JOURNAL OF CLINICAL INVESTIGATION (2010)
TGF-β activity protects against inflammatory aortic aneurysm progression and complications in angiotensin II-infused mice
Yu Wang et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
The Runx transcriptional co-activator, CBFβ, is essential for invasion of breast cancer cells
Daniel Mendoza-Villanueva et al.
MOLECULAR CANCER (2010)
Genomic analysis distinguishes phases of early development of the mouse atrio-ventricular canal
Pavle Vrljicak et al.
PHYSIOLOGICAL GENOMICS (2010)
Transcriptional Regulation of Heart Valve Progenitor Cells
Santanu Chakraborty et al.
PEDIATRIC CARDIOLOGY (2010)
Conditional inactivation of TGF-β type II receptor in smooth muscle cells and epicardium causes lethal aortic and cardiac defects
Dominique Langlois et al.
TRANSGENIC RESEARCH (2010)
Spatiotemporal expression of periostin during skin development and incisional wound healing: lessons for human fibrotic scar formation
Hong-Ming Zhou et al.
JOURNAL OF CELL COMMUNICATION AND SIGNALING (2010)
Genome-wide Association and Follow-Up Replication Studies Identified ADAMTS18 and TGFBR3 as Bone Mass Candidate Genes in Different Ethnic Groups
Dong-Hai Xiong et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2009)
Protective role of angiotensin II type 2 receptor signaling in a mouse model of pancreatic fibrosis
Barbara Ulmasov et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2009)
Calcific Aortic Stenosis Lessons Learned From Experimental and Clinical Studies
Nalini M. Rajamannan
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2009)
Interferon-γ and the Interferon-Inducible Chemokine CXCL10 Protect Against Aneurysm Formation and Rupture
Victoria L. King et al.
CIRCULATION (2009)
Origin of Cardiac Fibroblasts and the Role of Periostin
Paige Snider et al.
CIRCULATION RESEARCH (2009)
Adaptive and Maladptive Effects of SMAD3 Signaling in the Adult Heart After Hemodynamic Pressure Overloading
Vijay Divakaran et al.
CIRCULATION-HEART FAILURE (2009)
Impaired Systolic Function in Loeys-Dietz Syndrome A Novel Cardiomyopathy?
Peter M. Eckman et al.
CIRCULATION-HEART FAILURE (2009)
The regulation of TGFβ signal transduction
Aristidis Moustakas et al.
DEVELOPMENT (2009)
Endoglin is dispensable for angiogenesis, but required for endocardial cushion formation in the midgestation mouse embryo
Aya Nomura-Kitabayashi et al.
DEVELOPMENTAL BIOLOGY (2009)
TGF-β Superfamily Signaling in Embryonic Development and Homeostasis
Mary Y. Wu et al.
DEVELOPMENTAL CELL (2009)
Periostin Promotes a Fibroblastic Lineage Pathway in Atrioventricular Valve Progenitor Cells
Russell A. Norris et al.
DEVELOPMENTAL DYNAMICS (2009)
Ligand-Specific Function of Transforming Growth Factor Beta in Epithelial-Mesenchymal Transition in Heart Development
Mohamad Azhar et al.
DEVELOPMENTAL DYNAMICS (2009)
The expanding cardiovascular phenotype of Marfan syndrome
Julie De Backer
EUROPEAN JOURNAL OF ECHOCARDIOGRAPHY (2009)
Generation of Mice With a Conditional Allele for Transforming Growth Factor beta 1 Gene
Mohamad Azhar et al.
GENESIS (2009)
Absence of TGFβ Signaling in Embryonic Vascular Smooth Muscle Leads to Reduced Lysyl Oxidase Expression, Impaired Elastogenesis, and Aneurysm
Bibha Choudhary et al.
GENESIS (2009)
Aortic valve calcification: basic science to clinical practice
K. Akat et al.
HEART (2009)
An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice
Brian C. Tieu et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Analysis of multigenerational families with thoracic aortic aneurysms and dissections due to TGFBR1 or TGFBR2 mutations
V. Tran-Fadulu et al.
JOURNAL OF MEDICAL GENETICS (2009)
Molecular mechanisms underlying the onset of degenerative aortic valve disease
Daihiko Hakuno et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2009)
Syndromic and non-syndromic aneurysms of the human ascending aorta share activation of the Smad2 pathway
Delphine Gomez et al.
JOURNAL OF PATHOLOGY (2009)
AT1a receptor knockout in mice impairs urine concentration by reducing basal vasopressin levels and its receptor signaling proteins in the inner medulla
Xiao C. Li et al.
KIDNEY INTERNATIONAL (2009)
Plasma Levels of Transforming Growth Factor-β1 Reflect Left Ventricular Remodeling in Aortic Stenosis
Ana V. Villar et al.
PLOS ONE (2009)
Sequencing of TGF-beta Pathway Genes in Familial Cases of Intracranial Aneurysm
Teresa Santiago-Sim et al.
STROKE (2009)
Role of transforming growth factor-beta superfamily signaling pathways in human disease
Kelly J. Gordon et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2008)
Cancer-associated transforming growth factor β type II receptor gene mutant causes activation of bone morphogenic protein-Smads and invasive phenotype
Savita Bharathy et al.
CANCER RESEARCH (2008)
Report of the National Heart, Lung, and Blood Institute and National Marfan Foundation working group on research in Marfan syndrome and related disorders
Gail D. Pearson et al.
CIRCULATION (2008)
Periostin is required for maturation and extracellular matrix stabilization of noncardiomyocyte lineages of the heart
Paige Snider et al.
CIRCULATION RESEARCH (2008)
MEKK3 Initiates Transforming Growth Factor β2-Dependent Epithelial-to-Mesenchymal Transition During Endocardial Cushion Morphogenesis
Mark V. Stevens et al.
CIRCULATION RESEARCH (2008)
Periostin as a Heterofunctional Regulator of Cardiac Development and Disease
Simon J. Conway et al.
CURRENT GENOMICS (2008)
The intracellular renin-angiotensin system: implications in cardiovascular remodeling
Rajesh Kumar et al.
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2008)
Disruption of Smad4 in neural crest cells leads to mid-gestation death with pharyngeal arch, craniofacial and cardiac defects
Xuguang Nie et al.
DEVELOPMENTAL BIOLOGY (2008)
Twistl function in endocardial cushion cell proliferation, migration, and differentiation during heart valve development
Elaine L. Shelton et al.
DEVELOPMENTAL BIOLOGY (2008)
Periostin regulates atrioventricular valve maturation
Russell A. Norris et al.
DEVELOPMENTAL BIOLOGY (2008)
Signaling via the Tgf-β type I receptor Alk5 in heart development
Somyoth Sridurongrit et al.
DEVELOPMENTAL BIOLOGY (2008)
MAP3Ks as Central Regulators of Cell Fate During Development
Evisabel A. Craig et al.
DEVELOPMENTAL DYNAMICS (2008)
Two of four alternatively spliced isoforms of RUNX2 control osteocalcin gene expression in human osteoblast cells
Naoyuki Makita et al.
GENE (2008)
Uncoupling of chondrocyte differentiation and perichondrial mineralization underlies the skeletal dysplasia in tricho-rhino-phalangeal syndrome
Dobrawa Napierala et al.
HUMAN MOLECULAR GENETICS (2008)
How the Smads regulate transcription
Sarah Ross et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2008)
Multicenter research in adult congenital heart disease
Paul Khairy et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2008)
Bone morphogenetic proteins signal through the transforming growth factor-β type III receptor
Kellye C. Kirkbride et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Overexpression of transforming growth factor-β1 in the valvular fibrosis of chronic rheumatic heart disease
Lucia Kim et al.
JOURNAL OF KOREAN MEDICAL SCIENCE (2008)
Transforming Growth Factor β-Induced Smad1/5 Phosphorylation in Epithelial Cells Is Mediated by Novel Receptor Complexes and Is Essential for Anchorage-Independent Growth
Amanda C. Daly et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-β
Motozo Yamashita et al.
MOLECULAR CELL (2008)
Angiotensin II blockade and aortic-root dilation in Marfan's syndrome
Benjamin S. Brooke et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Perturbation of transforming growth factor (TGF)-ss1 association with latent TGF-β binding protein yields inflammation and tumors
Keiji Yoshinaga et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Functional role of periostin in development and wound repair: implications for connective tissue disease
Douglas W. Hamilton
JOURNAL OF CELL COMMUNICATION AND SIGNALING (2008)
Coronary vessel development is dependent on the type III transforming growth factor β receptor
Leigh A. Compton et al.
CIRCULATION RESEARCH (2007)
Rationale and design of a randomized clinical trial of β-blocker therapy (atenolol) versus angiotensin II receptor blocker therapy (losartan) in individuals with Marfan syndrome
Ronald V. Lacro et al.
AMERICAN HEART JOURNAL (2007)
TGF-β activates Erk MAP kinase signalling through direct phosphorylation of ShcA
Matt K. Lee et al.
EMBO JOURNAL (2007)
Differentiation plasticity regulated by TGF-β family proteins in development and disease
Rik Derynck et al.
NATURE CELL BIOLOGY (2007)
Myocardial Smad4 is essential for cardiogenesis in mouse embryos
Lanying Song et al.
CIRCULATION RESEARCH (2007)
Selective inhibitory effects of Smad6 on bone morphogenetic protein type I receptors
Kouichiro Goto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Genetic basis for congenital heart defects: Current knowledge - A scientific statement from the American heart association congenital cardiac defects committee, council on cardiovascular disease in the young
Mary Ella Pierpont et al.
CIRCULATION (2007)
Endoglin and Alk5 regulate epithelial-mesenchymal transformation during cardiac valve formation
Melania E. Mercado-Pimentel et al.
DEVELOPMENTAL BIOLOGY (2007)
Transforming growth factor-β1 mechanisms in aortic valve calcification:: Increased alkaline phosphatase and related events
Jocelyn N. Clark-Greuel et al.
ANNALS OF THORACIC SURGERY (2007)
Angiotensin II type 1 receptor blockade attenuates TGF-β-induced failure of muscle regeneration in multiple myopathic states
Ronald D. Cohn et al.
NATURE MEDICINE (2007)
Multimodality molecular imaging identifies proteolytic and osteogenic activities in early aortic valve disease
Elena Aikawa et al.
CIRCULATION (2007)
Mutations in the gene encoding filamin A as a cause for familial cardiac valvular dystrophy
Florence Kyndt et al.
CIRCULATION (2007)
Advances in Runx2 regulation and its isoforms
Ya-lin Li et al.
MEDICAL HYPOTHESES (2007)
Multiple transforming growth factor-beta isoforms and receptors function during epithelial-mesenchymal cell transformation in the embryonic heart
Melania E. Mercado-Pimentel et al.
CELLS TISSUES ORGANS (2007)
Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone
J. Pratap et al.
CANCER AND METASTASIS REVIEWS (2006)
Tgfβ signaling is required for atrioventricular cushion mesenchyme remodeling during in vivo cardiac development
Kai Jiao et al.
DEVELOPMENT (2006)
Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects
Jikui Wang et al.
BMC DEVELOPMENTAL BIOLOGY (2006)
Role of transforming growth factor-β in the progression of heart failure
H. Lim et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2006)
MEKK4 regulates developmental EMT in the embryonic heart
Mark V. Stevens et al.
DEVELOPMENTAL DYNAMICS (2006)
Aneurysm syndromes caused by mutations in the TGF-β receptor
Bart L. Loeys et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Overexpression of transforming growth factor-β is associated with increased hyaluronan content and impairment of repair in Marfan syndrome aortic aneurysm
Maria Nataatmadja et al.
CIRCULATION (2006)
Smad4 signalling in T cells is required for suppression of gastrointestinal cancer
Byung-Gyu Kim et al.
NATURE (2006)
Hearts and bones: Shared regulatory mechanisms in heart valve, cartilage, tendon, and bone development
Joy Lincoln et al.
DEVELOPMENTAL BIOLOGY (2006)
Major congenital malformations after first-trimester exposure to ACE inhibitors
William O. Cooper et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Human degenerative valve disease is associated with up-regulation of low-density lipoprotein receptor-related protein 5 receptor-mediated bone formation
FC Caira et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2006)
Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome
JP Habashi et al.
SCIENCE (2006)
Left ventricular diastolic dysfunction in children and young adults with Marfan syndrome
BB Das et al.
PEDIATRIC CARDIOLOGY (2006)
Mutations in the facilitative glucose transporter GLUT10 alter angiogenesis and cause arterial tortuosity syndrome
PJ Coucke et al.
NATURE GENETICS (2006)
Emilin1 links TGF-β maturation to blood pressure homeostasis
L Zacchigna et al.
CELL (2006)
The early history of TGF-β, and a brief glimpse of its future
MB Sporn
CYTOKINE & GROWTH FACTOR REVIEWS (2006)
Smad3 is key to TGF-β-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis
AB Roberts et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2006)
Characterization of SIS3, a novel specific inhibitor of Smad3, and its effect on transforming growth factor-β1-induced extracellular matrix expression
M Jinnin et al.
MOLECULAR PHARMACOLOGY (2006)
Periostin and periostin-like factor in the human heart: possible therapeutic targets
J Litvin et al.
CARDIOVASCULAR PATHOLOGY (2006)
Targeted disruption of Smad4 in cardiomyocytes results in cardiac hypertrophy and heart failure
J Wang et al.
CIRCULATION RESEARCH (2005)
The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion
J Pratap et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Angiotensin II activates the Smad pathway in vascular smooth muscle cells by a transforming growth factor-β-independent mechanism
J Rodríguez-Vita et al.
CIRCULATION (2005)
A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2
BL Loeys et al.
NATURE GENETICS (2005)
TGF-β receptor function in the endothelium
F Lebrin et al.
CARDIOVASCULAR RESEARCH (2005)
Regulatory mutations in transforming growth factor-β3 gene cause arrhythmogenic right ventricular cardiomyopathy type 1
G Beffagna et al.
CARDIOVASCULAR RESEARCH (2005)
TGF-β1 and angiotensin networking in cardiac remodeling
S Rosenkranz
CARDIOVASCULAR RESEARCH (2004)
Valvular myofibroblast activation by transforming growth factor-β -: Implications for pathological extracellular matrix remodeling in heart valve disease
GA Walker et al.
CIRCULATION RESEARCH (2004)
Heterozygous TGFBR2 mutations in Marfan syndrome
T Mizuguchi et al.
NATURE GENETICS (2004)
Angiotensin AT2 receptor contributes to cardiovascular remodelling of aged rats during chronic AT1 receptor blockade
ES Jones et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2004)
Cardiovascular and renal function of angiotensin II type-2 receptors
O Jöhren et al.
CARDIOVASCULAR RESEARCH (2004)
Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression
GS Stein et al.
ONCOGENE (2004)
Development of AT1 and AT2 receptors in the ovine fetal brain
F Hu et al.
DEVELOPMENTAL BRAIN RESEARCH (2004)
Selective deficiency of the bone-related Runx2-II unexpectedly preserves osteoblast-mediated skeletogenesis
ZS Xiao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Molecular markers of cardiac endocardial cushion development
AD Gitler et al.
DEVELOPMENTAL DYNAMICS (2003)
Transforming growth factor beta in cardiovascular development and function
M Azhar et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2003)
Stat1 functions as a attenuator of Runx2 in the transcriptional program of osteoblast cytoplasmic differentiation
S Kim et al.
GENES & DEVELOPMENT (2003)
Glycosaminoglycan myxomatous mitral profiles of leaflets and chordae parallel the severity of mechanical alterations
KJ Grande-Allen et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2003)
Expression patterns of Tgfβ1-3 associate with myocardialisation of the outflow tract and the development of the epicardium and the fibrous heart skeleton
DGM Molin et al.
DEVELOPMENTAL DYNAMICS (2003)
Heart and liver defects and reduced transforming growth factor β2 sensitivity in transforming growth factor β type III receptor-deficient embryos
KL Stenvers et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Human aortic valve calcification is associated with an osteoblast phenotype
NM Rajamannan et al.
CIRCULATION (2003)
The incidence of pediatric cardiomyopathy in two regions of the United States
SE Lipshultz et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
Dysregulation of TGF-β activation contributes to pathogenesis in Marfan syndrome
ER Neptune et al.
NATURE GENETICS (2003)
Progression of aortic valve stenosis:: TGF-β1 is present in calcified aortic valve cusps and promotes aortic valve interstitial cell calcification via apoptosis
B Jian et al.
ANNALS OF THORACIC SURGERY (2003)
Arrhythmogenic right ventricular cardiomyopathy type 1 (ARVD1): confirmation of locus assignment and mutation screening of four candidate genes
A Rampazzo et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2003)
Cbfβ interacts with Runx2 and has a critical role in bone development
M Kundu et al.
NATURE GENETICS (2002)
Serotonin mechanisms in heart valve disease I -: Serotonin-induced up-regulation of transforming growth factor-β1 via G-protein signal transduction in aortic valve interstitial cells
B Jian et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Tgfβ2-/-Tgfβ3-/- double knockout mice display severe midline fusion defects and early embryonic lethality
N Dünker et al.
ANATOMY AND EMBRYOLOGY (2002)
Temporal and distinct TGFβ ligand requirements during mouse and avian endocardial cushion morphogenesis
TD Camenisch et al.
DEVELOPMENTAL BIOLOGY (2002)
Mutations in the RUNX2 gene in patients with clelidocranial dysplasia
F Otto et al.
HUMAN MUTATION (2002)
TGFβ2 in corneal morphogenesis during mouse embryonic development
S Saika et al.
DEVELOPMENTAL BIOLOGY (2001)
Inhibition of transforming growth factor-β signaling accelerates atherosclerosis and induces an unstable plaque phenotype in mice
Z Mallat et al.
CIRCULATION RESEARCH (2001)
TGF-β1 gene polymorphisms in patients with end-stage heart failure
CTJ Holweg et al.
JOURNAL OF HEART AND LUNG TRANSPLANTATION (2001)
Filamin associates with Smads and regulates transforming growth factor-β signaling
A Sasaki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Periostin (an osteoblast-specific factor) is expressed within the embryonic mouse heart during valve formation
A Kruzynska-Frejtag et al.
MECHANISMS OF DEVELOPMENT (2001)
Developmentally regulated expression of Smad3, Smad4, Smad6, and Smad7 involved in TGF-beta signaling
K Luukko et al.
MECHANISMS OF DEVELOPMENT (2001)
Effects of gestation on ovine fetal and maternal angiotensin receptor subtypes in the heart and major blood vessels
JH Burrell et al.
EXPERIMENTAL PHYSIOLOGY (2001)
Targeted mutations of transforming growth factor-β genes reveal important roles in mouse development and adult homeostasis
N Dünker et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2000)
A RUNX2/PEBP2αA/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia
YW Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchyme
TD Camenisch et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
Delayed wound healing in immunodeficient TGF-β1 knockout mice
MJ Crowe et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2000)
Worldwide perspective of valve disease
J Soler-Soler et al.
HEART (2000)
Betaglycan binds inhibin and can mediate functional antagonism of activin signalling
KA Lewis et al.
NATURE (2000)
Mekk3 is essential for early embryonic cardiovascular development
JH Yang et al.
NATURE GENETICS (2000)
Endoglin, an ancillary TGF beta receptor, is required for extraembryonic angiogenesis and plays a key role in heart development
HM Arthur et al.
DEVELOPMENTAL BIOLOGY (2000)