相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Enhancement of an anti-tumor immune response by transient blockade of central T cell tolerance
Imran S. Khan et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility
Gregory Seumois et al.
NATURE IMMUNOLOGY (2014)
Extrathymic Aire-Expressing Cells Are a Distinct Bone Marrow-Derived Population that Induce Functional Inactivation of CD4+ T Cells
James M. Gardner et al.
IMMUNITY (2013)
High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
Yanfang Fu et al.
NATURE BIOTECHNOLOGY (2013)
Genome engineering using the CRISPR-Cas9 system
F. Ann Ran et al.
NATURE PROTOCOLS (2013)
Overlapping gene coexpression patterns in human medullary thymic epithelial cells generate self-antigen diversity
Sheena Pinto et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
Sven Malchow et al.
SCIENCE (2013)
Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection
Ruth T. Taniguchi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Post-Aire maturation of thymic medullary epithelial cells involves selective expression of keratinocyte-specific autoantigens
Xiaoping Wang et al.
FRONTIERS IN IMMUNOLOGY (2012)
Genomics of Long-Range Regulatory Elements
James P. Noonan et al.
ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, VOL 11 (2010)
Lymphotoxin Signals from Positively Selected Thymocytes Regulate the Terminal Differentiation of Medullary Thymic Epithelial Cells
Andrea J. White et al.
JOURNAL OF IMMUNOLOGY (2010)
Histone H3K27ac separates active from poised enhancers and predicts developmental state
Menno P. Creyghton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Diagnosis and Management of Polyendocrinopathy Syndromes
Catherine J. Owen et al.
ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA (2009)
Aire-Deficient C57BL/6 Mice Mimicking the Common Human 13-Base Pair Deletion Mutation Present with Only a Mild Autoimmune Phenotype
Francois-Xavier Hubert et al.
JOURNAL OF IMMUNOLOGY (2009)
ChIP-seq accurately predicts tissue-specific activity of enhancers
Axel Visel et al.
NATURE (2009)
Identification of an Autoantigen Demonstrates a Link Between Interstitial Lung Disease and a Defect in Central Tolerance
Anthony K. Shum et al.
SCIENCE TRANSLATIONAL MEDICINE (2009)
The cytokine RANKL produced by positively selected thymocytes Fosters medullary thymic epithelial cells that express autoimmune regulator
Yu Hikosaka et al.
IMMUNITY (2008)
The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance
Taishin Akiyama et al.
IMMUNITY (2008)
Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire
Maureen A. Su et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Deletional tolerance mediated by extrathymic Aire-expressing cells
James M. Gardner et al.
SCIENCE (2008)
RANK signals from CD4+3- inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla
Simona W. Rossi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Spontaneous autoimmunity prevented by thymic expression of a single self-antigen
Jason DeVoss et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
NF-κB2 is required for the establishment of central tolerance through an Aire-dependent pathway
Mingzhao Zhu et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
rVISTA 2.0: evolutionary analysis of transcription factor binding sites
GG Loots et al.
NUCLEIC ACIDS RESEARCH (2004)
VISTA: computational tools for comparative genomics
KA Frazer et al.
NUCLEIC ACIDS RESEARCH (2004)
Projection of an immunological self shadow within the thymus by the aire protein
MS Anderson et al.
SCIENCE (2002)
Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self
J Derbinski et al.
NATURE IMMUNOLOGY (2001)
分享论文
