期刊
CELL
卷 153, 期 2, 页码 287-292出版社
CELL PRESS
DOI: 10.1016/j.cell.2013.03.013
关键词
-
资金
- National Institutes of Health
Recent studies have revealed that multiple intracellular signaling proteins may assemble into structured, yet sometimes infinite, higher-order signaling machines for transmission of receptor activation information to cellular responses. These studies advance our understanding of cell signaling and implicate new molecular mechanisms in proximity-driven enzyme activation, threshold behavior, signal amplification, reduction of biological noise, and temporal and spatial control of signal transduction.
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