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The Long and Short of MicroRNA

期刊

CELL
卷 153, 期 3, 页码 516-519

出版社

CELL PRESS
DOI: 10.1016/j.cell.2013.04.003

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资金

  1. Cancer Research UK
  2. Oxford Division of Structural Biology is part of the Wellcome Trust Centre for Human Genetics, Wellcome Trust Core Award [090532/Z/09/Z]
  3. Cancer Research UK [13070] Funding Source: researchfish

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MicroRNAs (miRNAs) are versatile regulators of gene expression in higher eukaryotes. In order to silence many different mRNAs in a precise manner, miRNA stability and efficacy is controlled by highly developed regulatory pathways and fine-tuning mechanisms both affecting miRNA processing and altering mature miRNA target specificity.

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