期刊
CELL
卷 150, 期 5, 页码 873-875出版社
CELL PRESS
DOI: 10.1016/j.cell.2012.08.008
关键词
-
资金
- NINDS NIH HHS [P01NS050210, RC1 NS068280] Funding Source: Medline
Single-stranded RNAs interact with components of the RNA interference pathway to reduce the expression of target mRNAs. Now, Lima et al. and Yu et al. show that, with extensive chemical modifications, small single-stranded RNAs can robustly induce gene silencing with efficacy similar to their double-stranded counterparts.
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