期刊
CELL
卷 145, 期 1, 页码 15-17出版社
CELL PRESS
DOI: 10.1016/j.cell.2011.03.025
关键词
-
资金
- Telethon [GPP10005] Funding Source: Medline
Antiapoptotic Bcl-2 proteins on mitochondria inhibit prodeath proteins, such as Bax, which are found primarily in the cytosol. In this issue, Edlich et al., (2011) show that Bax and Bcl-xL interact on the mitochondrial surface and then retrotranslocate to the cytosol, effectively preventing Bax-induced permeabilization of mitochondria.
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