期刊
NATURE REVIEWS DRUG DISCOVERY
卷 2, 期 1, 页码 63-69出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrd986
关键词
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Target selection in drug discovery - defined here as the decision to focus on finding an agent with a particular biological action that is anticipated to have therapeutic utility - is influenced by a complex balance of scientific, medical and strategic considerations. In this article, we provide an introduction to the key issues in target selection and discuss the rationale for decision making.
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