4.8 Article

Understanding the Words of Chromatin Regulation

期刊

CELL
卷 136, 期 2, 页码 200-206

出版社

CELL PRESS
DOI: 10.1016/j.cell.2009.01.009

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资金

  1. Howard Hughes Medical Institute Funding Source: Medline
  2. NIAID NIH HHS [R01 AI060037, R01 AI060037-03, R01 AI060037-05, R01 AI060037-02, R01 AI060037-04, R01 AI060037-01] Funding Source: Medline
  3. NICHD NIH HHS [R01 HD055391] Funding Source: Medline
  4. NINDS NIH HHS [R01 NS046789, R01 NS046789-05, R01 NS046789-03, R01 NS046789-02, R01 NS046789-06, R01 NS046789-01, R01 NS046789-04] Funding Source: Medline

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Recent studies indicate that chromatin regulatory complexes produce biological specificity in the way that letters produce meanings by combinations into words. Combinatorial assembly of chromatin regulatory complexes may be critical for maximizing the information content provided by arrays of histone modifications.

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