Therapeutic use of Focus (R) Night & Day (TM) contact lenses

Purpose: To evaluate the safety and efficacy of Focus(R) Night Day(TM) extended-wear contact lenses when used for therapeutic purposes. Methods: Fifty eyes of 50 consecutive patients presenting at the Ankara University Medical Center, Cornea and Contact Lens Service, and requiring bandage contact lens use for ocular surface disorders, were enrolled. All patients were fitted with Focus(R) Night Day(TM) contact lenses and were followed in regard to patient satisfaction, contact lens flit and performance, and success of treatment. Results: Twenty-four patients (48%) were male, and 26 (52%) were female. Average age at the time of presentation was 46.9 +/- 21.6 years (range 1.5 to 88 years). Therapeutic contact lens indications included Fuchs, dystrophy (2 eyes), toxic epitheliopathy (1 eye), filamentous keratopathy (2 eyes), corneal perforation (2 eyes), corneal stromal melting (2 eyes), recurrent corneal erosion (4 eyes), chemical or traumatic epithelial defect (3 eyes), epithelial irregularity (1 eye), persistent epithelial defect (4 eyes), lamellar laceration (5 eyes), graft insufficiency (2 eyes), pseudophakic bullous keratopathy (7 eyes), aphakic bullous keratopathy (4 eyes), disciform keratitis (1 eye), postkeratectomy (4 eyes), and post-amniotic membrane transplantation or post-limbal autograft transplantation (6 eyes). Mean duration of continuous contact lens wear was 2.4 +/- 3.0 months (range 3 days to 12 months). At the end of the follow-up period, the mean change in visual acuity was a gain of 1.8 +/- 2.8 log-MAR units (0-9 Snellen lines). No sight-threatening complications related to contact lens wear were encountered. A culture-negative sterile corneal infiltrate developed in one patient and was treated with cessation of lens wear and subsequent topical antibiotic and steroids. Conclusion: Focus(R) Night Day(TM) contact lenses are safe and effective when used for therapeutic purposes. Infrequent replacement of these lenses seems to be especially advantageous in patients for whom frequent lens insertion and removal may be associated with epithelial trauma, pain, and a potential increase in infection risk. Infrequent replacement of these lenses also decreased the office time and the cost of treatment without an increase in hypoxia-related complications.