4.8 Article

Cancer cell metabolism: Warburg and beyond

期刊

CELL
卷 134, 期 5, 页码 703-707

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CELL PRESS
DOI: 10.1016/j.cell.2008.08.021

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资金

  1. NCI NIH HHS [R01 CA129105-02, R01 CA129105] Funding Source: Medline
  2. NIGMS NIH HHS [T32 GM007753] Funding Source: Medline

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Described decades ago, the Warburg effect of aerobic glycolysis is a key metabolic hallmark of cancer, yet its significance remains unclear. In this Essay, we re-examine the Warburg effect and establish a framework for understanding its contribution to the altered metabolism of cancer cells.

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