期刊
CELL
卷 134, 期 1, 页码 18-20出版社
CELL PRESS
DOI: 10.1016/j.cell.2008.06.039
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资金
- Medical Research Council [G117/569] Funding Source: Medline
- MRC [G117/569] Funding Source: UKRI
- Medical Research Council [G117/569] Funding Source: researchfish
Cell motility requires actin assembly mediated by Rac, a Rho family GTPase. In this issue, Palamidessi et al. (2008) show that Rab5-directed trafficking of Rac to the cell membrane is required for Rac-mediated actin assembly. Trafficking of Rac may influence the mode of cell migration during morphogenesis and cancer metastasis.
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