期刊
PARASITOLOGY
卷 129, 期 -, 页码 S161-S176出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0031182004004834
关键词
ticks; immunobiology; immunomodulation; saliva; genomics; proteomics
类别
资金
- NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [R01AI046676] Funding Source: NIH RePORTER
- NIAID NIH HHS [R01-AI46676] Funding Source: Medline
- ODCDC CDC HHS [U50/CCU119575] Funding Source: Medline
Ticks are of vast medical and veterinary public health importance due to direct damage Caused by feeding and their roles in transmitting well known and emerging infectious agents. Ticks and tick-borne pathogens stimulate the immune system of the host. Those immune interactions are of importance in tick biology, pathogen transmission and control of ticks and tick-borne diseases. Both innate and specific acquired immune defenses are involved in the responses of vertebrate hosts to infestation. Ticks have evolved countermeasures to Circumvent host immune defenses. This review addresses the immunobiology of the tick-host interface from the perspectives of the pharmacology of tick saliva; relationship of tick saliva to pathogen transmission; host immune responses to infestation; tick modulation of host immune defences; and genomic/ proteomic strategies for studying tick salivary gland molecules.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据