期刊
AMERICAN NATURALIST
卷 163, 期 1, 页码 84-96出版社
UNIV CHICAGO PRESS
DOI: 10.1086/380570
关键词
comparative method; mixed model; phenotypic evolution; phylogenetic analysis; phylogenetic heritability; quantitative genetics
资金
- NIGMS NIH HHS [GM36827] Funding Source: Medline
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM036827] Funding Source: NIH RePORTER
The phylogenetic mixed model is an application of the quantitative-genetic mixed model to interspecific data. Although this statistical framework provides a potentially unifying approach to quantitative-genetic and phylogenetic analysis, the model has been applied infrequently because of technical difficulties with parameter estimation. We recommend a reparameterization of the model that eliminates some of these difficulties, and we develop a new estimation algorithm for both the original maximum likelihood and new restricted maximum likelihood estimators. The phylogenetic mixed model is particularly rich in terms of the evolutionary insight that might be drawn from model parameters, so we also illustrate and discuss the interpretation of the model parameters in a specific comparative analysis.
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