Cell biology of the intracellular infection by Legionella pneumophila

Legionella pneumophila has become a paradigm for facultative intracellular pathogens that modulate biogenesis of their phagosomes into replicative niches. The ability to alter host cell biology and tailor it into a hospitable host for intracellular proliferation is at the crux of the mechanism of pathogenesis of Legionnaires' disease. (C) 2003 Elsevier SAS. All rights reserved.