期刊
ORGANIC PROCESS RESEARCH & DEVELOPMENT
卷 8, 期 1, 页码 101-106出版社
AMER CHEMICAL SOC
DOI: 10.1021/op0341317
关键词
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Kilogram-scale syntheses of fragments C1-6 (6) and C9-14 (4) of (+)-discodermolide from common precursor 3 are described. Improved procedures for each step of both fragments were developed by minimizing or eliminating the formation of byproducts that were isolated and characterized in Smith's synthesis.
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