期刊
INTERNATIONAL JOURNAL OF NEUROSCIENCE
卷 114, 期 1, 页码 95-104出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/00207450490249347
关键词
alternation; impulsivity; inhibition; orbitofrontal; prefrontal
Impulsivity is associated with the functioning of prefrontal-subcortical circuits particularly, the orbitofrontal circuit, which is shown in neuro-imaging studies of neurological and psychological disorders. Objective behavioral measures, such as go/no-go, antisaccades, and delayed alternation, have demonstrated sensitivity to prefrontal function. This study examined the relationship between orbitofrontal-sensitive measures and impulsivity in healthy adults, as measured by the Barratt Impulsiveness Scale-11 (BIS). Go/no-go and antisaccades correlated positively and delayed alternations correlated negatively with BIS subscales, even after controlling for demographic influences. The results add to the validity of the BIS and support a role for prefrontal cortex in impulse control.
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