期刊
JOURNAL OF EXPERIMENTAL BIOLOGY
卷 218, 期 18, 页码 2826-2829出版社
COMPANY BIOLOGISTS LTD
DOI: 10.1242/jeb.125203
关键词
Melanopsin; Lateral line; Mechanoreceptor; Photosensitivity; Multimodality; Phototaxis
类别
资金
- European Office of Aerospace Research Development [F61708-98-W0026]
- Wellcome Trust [090684/Z/09/Z, 098461/Z/12/Z]
- Wellcome Trust [090684/Z/09/Z] Funding Source: Wellcome Trust
Using immunohistochemistry and western blot analysis, we demonstrate that melanopsin is localised in cells around the central pore of lateral line neuromasts in the African clawed frog, Xenopus laevis. Since melanopsin is a known photoreceptor pigment with diverse functions in vertebrates, we suggest that the lateral line of Xenopus laevis, which is primarily a mechanoreceptor, might also be light sensitive. Potential functions of such photosensitivity are discussed, including its role in mediating locomotor responses following dermal illumination.
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