期刊
COMMUNITY GENETICS
卷 7, 期 4, 页码 202-210出版社
KARGER
DOI: 10.1159/000082263
关键词
apolipoprotein E; genetic testing; older adults; participant recruitment; race
资金
- NIMH NIH HHS [R01 MH062210-01, MH62210-01, R01 MH062210-01S1, MH62210-01S1, K23 MH067671-01, MH67077, MH67671-01, R01 MH067077, R01 MH067077-01, R01 MH062210, K23 MH067671] Funding Source: Medline
- NATIONAL INSTITUTE OF MENTAL HEALTH [K23MH067671, R01MH062210, R01MH067077] Funding Source: NIH RePORTER
Objective:To determine the personal characteristics and reasons associated with providing a buccal swab for apolipoprotein E (APOE) genetic testing in a primary care study. Methods: The study sample consisted of 342 adults aged 65 years and older recruited from primary care settings. Results: In all, 88% of patients agreed to provide a DNA sample for APOE genotyping and 78% of persons providing a sample agreed to banking of the DNA. Persons aged 80 years and older and African-Americans were less likely to participate in APOE genotyping. Concern about confidentiality was the most common reason for not wanting to provide a DNA sample or to have DNA banked. Conclusion: We found stronger relationships between sociodemographic variables of age and ethnicity with participation in genetic testing than we did between level of educational attainment, gender, function, cognition, and affect. Copyright © 2004 S. Karger AG, Basel.
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