Scolecite as a novel heterogeneous acid catalyst for an efficient synthesis of 3,4-dihydropyrimidin-2(1H)-ones via multi-component Biginelli reaction

Scolecite is one kind of natural zeolite. A three component Biginelli reaction using scolecite as a novel heterogeneous acid catalyst is demonstrated. The short reaction time, clean reaction conditions, consistent yields and minimum environmental effects are important features of the reaction.