Colistin for Klebsiella pneumoniae-associated sepsis

Klebsiella pneumoniae that was resistant to all available antibiotics ( minimum inhibitory concentration of imipenem, 32 mug/ mL), including carbapenems, was isolated from blood samples obtained from a 48- year- old patient in the intensive care unit. The patient developed septic shock, which was successfully treated with colistin, the only antibiotic with activity against this multidrug- resistant strain.