期刊
APPLIED OPTICS
卷 43, 期 1, 页码 113-121出版社
OPTICAL SOC AMER
DOI: 10.1364/AO.43.000113
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资金
- NATIONAL CANCER INSTITUTE [R24CA083148] Funding Source: NIH RePORTER
- NCI NIH HHS [CA83148] Funding Source: Medline
We have designed a multimodality system that combines optical coherence tomography (OCT) and laser-induced fluorescence (LIF) in a 2.0-mm-diameter endoscopic package. OCT provides similar to18-mum resolution cross-sectional structural information over a 6-mm field. LIF spectra are collected sequentially at submillimeter resolution across the same field and provide histochemical. information about the tissue. We present the use of a rod prism to reduce the asymmetry in the OCT beam caused by a cylindrical window. The endoscope has been applied to investigate mouse colon cancer in vivo. (C) 2004 Optical Society of America.
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