期刊
VISION RESEARCH
卷 44, 期 22, 页码 2559-2566出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.visres.2004.05.025
关键词
visual acuity; transplantation; Schwann cells; retinal pigment epithelium; retinal dystrophy
This Study examines whether subretinal transplantation of a human retinal pigment epithelial cell line (ARPE19) or human Schwann cells early in the course of degeneration can limit the loss of visual acuity that normally Occurs in dystrophic Royal College of Surgeons (RCS) rats as they age. The acuity of both transplanted groups was significantly better than controls at all ages tested, though the rescue profile of each cell type was unique. These data indicate that the transplantation of cells with very different phenotypes can be used to limit the deterioration of spatial vision in an animal model of retinal degenerative disease. (C) 2004 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据