期刊
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
卷 51, 期 1, 页码 90-99出版社
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TBME.2003.820329
关键词
adaptive beamformer; biomagnetism; functional neuroimaging; magnetoencephalography; MEG inverse problems; neuromagnetic signal processing
资金
- NATIONAL CENTER FOR RESEARCH RESOURCES [P41RR012553] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS [R01DC005660, R01DC004855] Funding Source: NIH RePORTER
- NCRR NIH HHS [P41RR12553-03] Funding Source: Medline
- NIDCD NIH HHS [R01-DC004855-01A1, R01-DC5660] Funding Source: Medline
The influence of external interference on neuromagnetic source reconstruction by adaptive beamformer techniques was investigated. In our analysis, we assume that the interference has the following two properties: First, it is additive and uncorrelated with brain activity. Second, its temporal behavior can be characterized by a few distinct activities, and as a result, the spatio-temporal matrix of the interference has a few distinctly large singular values. Namely, the interference can be modeled as a low-rank signal. Under these assumptions, our analysis shows that the adaptive beamformer techniques are insensitive to interference when its spatial singular vectors are so different from a lead field vector of a brain source that the generalized cosine between these two vectors is much smaller than unity. Four types of numerical examples verifying this conclusion are presented.
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