DNA biochip arraying, detection and amplification strategies

Research on DNA biochips is advancing rapidly and has yielded several commercial platforms. This review presents, critically comments upon and compares DNA-biochip-arraying methods and techniques. it also discusses methods for detecting and amplifying hybridization events. The review focuses on miniaturization of these systems for diagnostic applications of biochip technology. (C) 2003 Published by Elsevier B.V.