期刊
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
卷 35, 期 1, 页码 198-202出版社
SPRINGER
DOI: 10.1007/s00270-011-0145-7
关键词
Interventional oncology; Chemoembolization/chemoembolisation; Embolization/embolisation/embolotherapy; Transarterial chemoembolization/embolisation (TACE); Liver/hepatic; Hepatocellular carcinoma (HCC); Tumor/tumour/neoplasm
Spontaneous rupture of hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE) is a rare and life-threatening complication. Pathophysiologic mechanisms are not yet fully known; it is suggested that rupture is preceded by reactive tissue edema and intratumerous bleeding, leading to a rapid expansion of tumour mass with risk of extrahepatic bleeding in the case of subcapsular localisation. This case report discusses a sudden, unexpected lethal complication in a 74 year-old male patient treated with TACE using DC Bead loaded with doxorubicin (DEBDOX) in a progressive multifocal HCC.
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