期刊
NATURE REVIEWS MOLECULAR CELL BIOLOGY
卷 6, 期 9, 页码 715-725出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrm1714
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资金
- NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES [Z01DK061000, ZIADK061000] Funding Source: NIH RePORTER
- Intramural NIH HHS Funding Source: Medline
Unique developmental features during puberty, pregnancy, lactation and post-lactation make the mammary gland a prime object to explore genetic circuits that control the specification, proliferation, differentiation, survival and death of cells. Steroids and simple peptide hormones initiate and carry out complex developmental programmes, and reverse genetics has been used to define the underlying mechanistic connections.
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