期刊
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
卷 19, 期 5, 页码 552-555出版社
BLACKWELL PUBLISHING
DOI: 10.1111/j.1468-3083.2005.01226.x
关键词
8-methoxypsoralen; alopecia areata; alopecia totalis; alopecia universalis; phototherapy; PUVA
类别
Twenty-five patients with alopecia totalis (AT) or alopecia universalis and 124 patients with alopecia areata (AA) were treated with photochemotherapy, combining topical 8-methoxypsoralen (8-MOP) with UV irradiation of the scalp at a phototoxic dose. The mean energy required was 15 J/cm(2) for AA and 42 J/cm(2) for AT. Ninety-four patients had multiple bald patches and 12 with AT had complete or >50% hair regrowth. Positive treatment results did not seem to depend on the age of onset or the duration of the disease. Few side-effects of topical psoralens plus UVA (PUVA) treatment were noted, except a for few days of slight erythema caused by the high dose of UV.
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