4.7 Article

Effects of the cell geometry and operating parameters on the performance of an external contactless conductivity detector for microchip electrophoresis

向作者/读者索取更多资源

Quantitative data on the effect of the electrode geometry on the signal strength and the signal-to-noise ratio is given. The measurements are affected by the unavoidable presence of stray capacitance. Best results are achieved for short and narrow electrodes arranged in an antiparallel configuration and separated by a minimal gap, which determines the dimensions of the actual detection volume. Limits of detection between 150 and 250 mu g l(-1) and separation efficiencies from 13 000 to 17 000 theoretical plates were achieved for six inorganic cations (NH4+, K+, Ca2+, Na+, Mg2+ and Li+) with electrodes of 1 mm width and a detection gap of 0.5 mm ( separation channel length: 7.5 cm) when operating the detector at 20 V-pp and 500 kHz. The analyses of all major inorganic cations in tap and rain water samples were demonstrated for the first time in microchip electrophoresis with contactless conductivity detection.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据