期刊
JOURNAL OF HETEROCYCLIC CHEMISTRY
卷 42, 期 1, 页码 61-66出版社
WILEY
DOI: 10.1002/jhet.5570420108
关键词
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The synthesis of a series of bis-pyrazolo[3,4-b:4',3'-e]pyridines (3) in the reaction of 5-amino-3-methyl-1-phenylpyrazole (1) with aldehydes (2) under microwave irradiation and solvent-free conditions is described. The structure elucidation of the products is based on detailed nmr analysis of experiments such as I H-COSY, NOESY, DEPT, HSQC and HMBC. These compounds showed moderate antifungal in vitro activity against dermatophytes.
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