期刊
CONTRACEPTION
卷 71, 期 1, 页码 1-7出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.contraception.2004.07.010
关键词
oral contraceptive; drospirenone; levonorgestrel; premenstrual symptoms
This open-label randomized study compared the effects of two combined oral contraceptives (OCs) containing 3 me drospirenone (DRSP)/30 mug ethinyl estradiol (EE) with 150 mug levonorgestrel (LING)/30 mug EE on the prevalence and changes from baseline of premenstrual symptoms after six cycles. The symptoms were measured using the Women's Health Assessment Questionnaire. Subjects receiving DRSP/EE had fewer prevalence of premenstrual symptoms than those receiving LNG/EE after six cycles. A significantly lower score of negative affect category in the premenstrual phase was demonstrated in those receiving DRSP/EE more than LNG/EE. The DRSP/EE group showed a greater improvement of mean scores from baseline in the premenstrual phase compared with those who received LNG/EE on negative affect as seen in the items on anxiety, irritability, feeling sad or blue and weight gain in the category of water retention. In conclusion, OCs containing DRSP have beneficial effects in reducing the prevalence of premenstrual symptoms especially the symptoms of negative affect and weight gain.. particularly when compared to LNG/EE. Hence. it should be recommended for women who are susceptible to these adverse symptoms. (C) 2005 Elsevier Inc. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据