期刊
TRENDS IN BIOCHEMICAL SCIENCES
卷 30, 期 9, 页码 506-514出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibs.2005.07.005
关键词
-
资金
- Cancer Research UK [A6517] Funding Source: Medline
- Wellcome Trust [077118] Funding Source: Medline
Gene expression is regulated at multiple levels, and cells need to integrate and coordinate different layers of control to implement the information in the genome. Post-transcriptional levels of regulation such a's transcript turnover and translational control are an,integral part of gene expression and might rival the sophistication and importance of transcriptional control. Microarray-based methods are increasingly used to study not only transcription but also global patterns of transcript decay and translation rates in addition to comprehensively identify targets of RNA-binding proteins. Such large-scale analyses have recently provided supplementary and unique insights into gene expression programs. Integration of several different datasets will ultimately lead to a system-wide understanding of the varied and complex mechanisms for gene expression control.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据