期刊
CARDIOLOGY
卷 113, 期 1, 页码 12-19出版社
KARGER
DOI: 10.1159/000164149
关键词
Diuretics; Acute Decompensated Heart Failure National Registry; Creatinine; Glomerular filtration rate
The optimal use of diuretics in decompensated heart failure remains uncertain. We analyzed data from the ADHERE registry to look at the impact of diuretic dosing. 62,866 patients receiving <160 mg and 19,674 patients >= 160 mg of furosemide were analyzed. The patients receiving the lower doses had a lower risk for in-hospital mortality, ICU stay, prolonged hospitalization, or adverse renal effects. These findings suggest that future studies should evaluate strategies for minimizing exposure to high doses of diuretics. Copyright (C) 2008 S. Karger AG, Basel
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