相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Animal Models of Human Prostate Cancer: The Consensus Report of the New York Meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee
Michael Ittmann et al.
CANCER RESEARCH (2013)
Targeting the PI3K/Akt/mTOR pathway in castration-resistant prostate cancer
Rhonda L. Bitting et al.
ENDOCRINE-RELATED CANCER (2013)
Phase 2 Trial of Single-agent Everolimus in Chemotherapy-naive Patients with Castration-resistant Prostate Cancer (SAKK 08/08)
Arnoud J. Templeton et al.
EUROPEAN UROLOGY (2013)
Genetically engineered mouse models of prostate cancer
Maxime Parisotto et al.
MOLECULAR ONCOLOGY (2013)
Plasticity of tumour and immune cells: a source of heterogeneity and a cause for therapy resistance?
Michael Hoelzel et al.
NATURE REVIEWS CANCER (2013)
Phase II trial of RAD001 and bicalutamide for castration-resistant prostate cancer
Mari Nakabayashi et al.
BJU INTERNATIONAL (2012)
Dual Targeting of the Akt/mTOR Signaling Pathway Inhibits Castration-Resistant Prostate Cancer in a Genetically Engineered Mouse Model
Nicolas Floc'h et al.
CANCER RESEARCH (2012)
Pten Loss and RAS/MAPK Activation Cooperate to Promote EMT and Metastasis Initiated from Prostate Cancer Stem/Progenitor Cells
David J. Mulholland et al.
CANCER RESEARCH (2012)
Persistent androgen receptor-mediated transcription in castration-resistant prostate cancer under androgen-deprived conditions
Keith F. Decker et al.
NUCLEIC ACIDS RESEARCH (2012)
Preclinical Remodeling of Human Prostate Cancer through the PTEN/AKT Pathway
Marco A. De Velasco et al.
ADVANCES IN UROLOGY (2012)
Cell Autonomous Role of PTEN in Regulating Castration-Resistant Prostate Cancer Growth
David J. Mulholland et al.
CANCER CELL (2011)
Reciprocal Feedback Regulation of PI3K and Androgen Receptor Signaling in PTEN-Deficient Prostate Cancer
Brett S. Carver et al.
CANCER CELL (2011)
Androgen receptor levels are upregulated by Akt in prostate cancer
Susan Ha et al.
ENDOCRINE-RELATED CANCER (2011)
Regulation, Role, and Targeting of Akt in Cancer
Michael A. Davies
JOURNAL OF CLINICAL ONCOLOGY (2011)
Androgen Receptor Rediscovered: The New Biology and Targeting the Androgen Receptor Therapeutically
Charles J. Ryan et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma
Jonathan H. Schatz et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
MEK/ERK Inhibitor U0126 Increases the Radiosensitivity of Rhabdomyosarcoma Cells In vitro and In vivo by Downregulating Growth and DNA Repair Signals
Francesco Marampon et al.
MOLECULAR CANCER THERAPEUTICS (2011)
SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression
Zhihu Ding et al.
NATURE (2011)
mTOR Kinase Inhibition Causes Feedback-Dependent Biphasic Regulation of AKT Signaling
Vanessa S. Rodrik-Outmezguine et al.
CANCER DISCOVERY (2011)
A Pharmacodynamic Study of Rapamycin in Men with Intermediate- to High-Risk Localized Prostate Cancer
Andrew J. Armstrong et al.
CLINICAL CANCER RESEARCH (2010)
mTOR Complex 2 Is Required for the Development of Prostate Cancer Induced by Pten Loss in Mice
David A. Guertin et al.
CANCER CELL (2009)
Inhibition of Tumor Growth Progression by Antiandrogens and mTOR Inhibitor in a Pten-Deficient Mouse Model of Prostate Cancer
Weisheng Zhang et al.
CANCER RESEARCH (2009)
PTEN, Stem Cells, and Cancer Stem Cells
Reginald Hill et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Is PTEN loss associated with clinical outcome measures in human prostate cancer?
P. McCall et al.
BRITISH JOURNAL OF CANCER (2008)
Targeting prostate cancer based on signal transduction and cell cycle pathways
John T. Lee et al.
CELL CYCLE (2008)
Targeting AKT/mTOR and ERK MAPK signaling inhibits hormone-refractory prostate cancer in a preclinical mouse model
Carolyn Waugh Kinkade et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Delivery of PTEN via a novel gene microcapsule sensitizes prostate cancer cells to irradiation
Atsushi Tomioka et al.
MOLECULAR CANCER THERAPEUTICS (2008)
Evolvable signaling networks of receptor tyrosine kinases: relevance of robustness to malignancy and to cancer therapy
Ido Amit et al.
MOLECULAR SYSTEMS BIOLOGY (2007)
FISH analysis of 107 prostate cancers shows that PTEN genomic deletion is associated with poor clinical outcome
M. Yoshimoto et al.
BRITISH JOURNAL OF CANCER (2007)
Genetic background controls tumor development in Pten-deficient mice
Dan Freeman et al.
CANCER RESEARCH (2006)
The negative regulation of phosphoinositide 3-kinase signaling by p85 and it's implication in cancer
J Luo et al.
CELL CYCLE (2005)
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
ZB Chen et al.
NATURE (2005)
Targeted biallelic inactivation of Pten in the mouse prostate leads to prostate cancer accompanied by increased epithelial cell proliferation but not by reduced apoptosis
XQ Ma et al.
CANCER RESEARCH (2005)
Prostate pathology of genetically engineered mice: Definitions and classification. The consensus report from the bar harbor meeting of the mouse models of human cancer consortium prostate pathology committee
SB Shappell et al.
CANCER RESEARCH (2004)
Opinon - Cancer as a robust system: implications for anticancer therapy
H Kitano
NATURE REVIEWS CANCER (2004)
mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways
PK Majumder et al.
NATURE MEDICINE (2004)
Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer
SY Wang et al.
CANCER CELL (2003)
Phenotypic heterogeneity of end-stage prostate carcinoma metastatic to bone
MP Roudier et al.
HUMAN PATHOLOGY (2003)
Conditional loss of Nkx3.1 in adult mice induces prostatic intraepithelial neoplasia
SA Abdulkadir et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice
K Podsypanina et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
T cell-specific loss of Pten leads to defects in central and peripheral tolerance
A Suzuki et al.
IMMUNITY (2001)
分享论文
