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Ping-yuan Wang et al.
CURRENT OPINION IN ONCOLOGY (2012)
Understanding the structural ensembles of a highly extended disordered protein
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MOLECULAR BIOSYSTEMS (2012)
Distinct p53 Transcriptional Programs Dictate Acute DNA-Damage Responses and Tumor Suppression
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p53 regulation by ubiquitin
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Cancer Susceptibility Polymorphism of p53 at Codon 72 Affects Phosphorylation and Degradation of p53 Protein
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JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Peptide-Protein Interactions Suggest That Acetylation of Lysines 381 and 382 of p53 Is Important for Positive Coactivator 4-p53 Interaction
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JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
The role of mutant p53 in human cancer
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Genotoxic exposure: novel cause of selection for a functional ΔN-p53 isoform
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Role of p53 Serine 46 in p53 Target Gene Regulation
Leonie Smeenk et al.
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Loss of p53 Ser18 and Atm Results in Embryonic Lethality without Cooperation in Tumorigenesis
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PLOS ONE (2011)
Protein-Protein Interactions Occur Between p53 Phosphoforms and ATM and 53BP1 at Sites of Exogenous DNA Damage
Shahnaz T. Al Rashid et al.
RADIATION RESEARCH (2011)
The impact of acetylation and deacetylation on the p53 pathway
Christopher L. Brooks et al.
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Nitration of the Tumor Suppressor Protein p53 at Tyrosine 327 Promotes p53 Oligomerization and Activation
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BIOCHEMISTRY (2010)
Structure of the p53 Transactivation Domain in Complex with the Nuclear Receptor Coactivator Binding Domain of CREB Binding Protein
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BIOCHEMISTRY (2010)
Keeping p53 in Check: A High-Stakes Balancing Act
Shelley L. Berger
CELL (2010)
Δ40p53 controls the switch from pluripotency to differentiation by regulating IGF signaling in ESCs
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GENES & DEVELOPMENT (2010)
Regulation of the p53 pathway by ubiquitin and related proteins
Andreas Hock et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2010)
Requirement of the ATM/p53 Tumor Suppressor Pathway for Glucose Homeostasis
Heather L. Armata et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
Endoplasmic Reticulum Stress Induces G2 Cell-Cycle Arrest via mRNA Translation of the p53 Isoform p53/47
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Puma is required for p53-induced depletion of adult stem cells
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NATURE CELL BIOLOGY (2010)
Graded enhancement of p53 binding to CREB-binding protein (CBP) by multisite phosphorylation
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Mapping the physical and functional interactions between the tumor suppressors p53 and BRCA2
Sridharan Rajagopalan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
p53 post-translational modification: deregulated in tumorigenesis
Chao Dai et al.
TRENDS IN MOLECULAR MEDICINE (2010)
Transcriptional Regulation by p53
Rachel Beckerman et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)
Two Distinct Motifs within the p53 Transactivation Domain Bind to the Taz2 Domain of p300 and Are Differentially Affected by Phosphorylation
Lisa M. Miller Jenkins et al.
BIOCHEMISTRY (2009)
Mapping the Interactions of the p53 Transactivation Domain with the KIX Domain of CBP
Chul Won Lee et al.
BIOCHEMISTRY (2009)
Limitations of Induced Folding in Molecular Recognition by Intrinsically Disordered Proteins
Eszter Hazy et al.
CHEMPHYSCHEM (2009)
Interaction between the Transactivation Domain of p53 and PC4 Exemplifies Acidic Activation Domains as Single-stranded DNA Mimics
Sridharan Rajagopalan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
SMAR1 Forms a Ternary Complex with p53-MDM2 and Negatively Regulates p53-mediated Transcription
Lakshminarasimhan Pavithra et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
Physical and functional interactions between human mitochondrial single-stranded DNA-binding protein and tumour suppressor p53
Tuck Seng Wong et al.
NUCLEIC ACIDS RESEARCH (2009)
Transcription activity is required for p53-dependent tumor suppression
O. Gaidarenko et al.
ONCOGENE (2009)
Regulation by phosphorylation of the relative affinities of the N-terminal transactivation domains of p53 for p300 domains and Mdm2
D. P. Teufel et al.
ONCOGENE (2009)
Cooperative regulation of p53 by modulation of ternary complex formation with CBP/p300 and HDM2
Josephine C. Ferreon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
The rules of disorder or why disorder rules
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PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2009)
Structural Basis for p300 Taz2-p53 TAD1 Binding and Modulation by Phosphorylation
Hanqiao Feng et al.
STRUCTURE (2009)
Posttranslational Modification of p53: Cooperative Integrators of Function
David W. Meek et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2009)
Genome-wide analysis of the interaction between the endosymbiotic bacterium Wolbachia and its Drosophila host
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BMC GENOMICS (2008)
Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence
Kensuke Kumamoto et al.
CANCER RESEARCH (2008)
The electrostatic surface of MDM2 modulates the specificity of its interaction with phosphorylated and unphosphorylated p53 peptides
Christopher John Brown et al.
CELL CYCLE (2008)
Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain
Grzegorz M. Popowicz et al.
CELL CYCLE (2008)
Differential recognition of phosphorylated transactivation domains of p53 by different p300 domains
Smarajit Polley et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Inhibition of Thr-55 phosphorylation restores p53 nuclear localization and sensitizes cancer cells to DNA damage
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Serine 15 phosphorylation of p53 directs its interaction with B56 gamma and the tumor suppressor activity of B56 gamma-specific protein phosphatase 2A
Geoffrey P. Shouse et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
The ataxia telangiectasia-mutated target site Ser18 is required for p53-mediated tumor suppression
Heather L. Armata et al.
CANCER RESEARCH (2007)
Modulation of the p53-MDM2 interaction by phosphorylation of Thr18 - A computational study
Hui Jun Lee et al.
CELL CYCLE (2007)
Molecular basis for the inhibition of p53 by Mdmx
Grzegorz M. Popowicz et al.
CELL CYCLE (2007)
Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype:: Lessons from recent developments in the IARC TP53 database
Audrey Petitjean et al.
HUMAN MUTATION (2007)
Identifying long-range structure in the intrinsically unstructured transactivation domain of p53
Pamela Vise et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2007)
Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53
Daniel P. Teufel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Integration of TGF-β and Ras/MAPK signaling through p53 phosphorylation
Michelangelo Cordenonsi et al.
SCIENCE (2007)
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Rieko Ohki et al.
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Ser46 phosphorylation regulates p53-dependent apoptosis and replicative senescence
Lijin Feng et al.
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Repression of p53 activity by Smyd2-mediated methylation
Jing Huang et al.
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Structure of the Tfb1/p53 complex: Insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53
Paola Di Lello et al.
MOLECULAR CELL (2006)
Ubiquitination of p53 at multiple sites in the DNA-binding domain
WM Chan et al.
MOLECULAR CANCER RESEARCH (2006)
Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A
E Bochkareva et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
p53QS -: An old mutant teaches us new tricks
TM Johnson et al.
CELL CYCLE (2005)
The p53QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality
TM Johnson et al.
NATURE GENETICS (2005)
Phosphorylation of serine 18 regulates distinct p53 functions in mice
HK Sluss et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Defective apoptosis and B-cell lymphomas in mice with p53 point mutation at Ser 23
D MacPherson et al.
EMBO JOURNAL (2004)
Association of Ubc9, an E2 ligase for SUMO conjugation, with p53 is regulated by phosphorylation of p53
JY Lin et al.
FEBS LETTERS (2004)
Phosphorylation of p53 on key serines is dispensable for transcriptional activation and apoptosis
T Thompson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity
DP Xirodimas et al.
CELL (2004)
Regulation of p53 activity through lysine methylation
S Chuikov et al.
NATURE (2004)
HCMV IE2-mediated inhibition of HAT activity downregulates p53 function
CH Hsu et al.
EMBO JOURNAL (2004)
Cell type- and promoter-specific roles of Ser18 phosphorylation in regulating p53 responses
C Chao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Phosphorylation site interdependence of human p53 post-translational modifications in response to stress
S Saito et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The activation domains, the proline-rich domain, and the C-terminal basic domain in p53 are necessary for acetylation of histones on the proximal p21 promoter and interaction with p300/CREB-binding protein
G Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
DNA-dependent acetylation of p53 by the transcription coactivator p300
D Dornan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
p53 transcriptional activity is mediated through the SRC1-interacting domain of CBP/p300
JA Livengood et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases
NA Barlev et al.
MOLECULAR CELL (2001)
Negative control of p53 by Sir2α promotes cell survival under stress
JY Luo et al.
CELL (2001)
hSIR2SIRT1 functions as an NAD-dependent p53 deacetylase
H Vaziri et al.
CELL (2001)
Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment
JM Espinosa et al.
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Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation
MS Rodriguez et al.
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