4.6 Article

A small molecule focal adhesion kinase (FAK) inhibitor, targeting Y397 site: 1-(2-hydroxyethyl)-3, 5, 7-triaza-1-azoniatricyclo [3.3.1.13,7]decane; bromide effectively inhibits FAK autophosphorylation activity and decreases cancer cell viability, clonogenicity and tumor growth in vivo

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Cell Biology

Inhibition of focal adhesion kinase decreases tumor growth in human neuroblastoma

Elizabeth A. Beierle et al.

CELL CYCLE (2010)

Review Pharmacology & Pharmacy

Therapeutic potential and limitations of new FAK inhibitors in the treatment of cancer

Alexander Schultze et al.

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2010)

Review Cell Biology

The FERM domain: organizing the structure and function of FAK

Margaret C. Frame et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)

Article Biochemistry & Molecular Biology

TAE2264-induced apoptosis in breast cancer cells with overexpressed Src or EGFR

Vita M. Golubovskaya et al.

MOLECULAR CARCINOGENESIS (2008)

Article Biochemistry & Molecular Biology

P53 regulates FAK expression in human tumor cells

Vita M. Golubovskaya et al.

MOLECULAR CARCINOGENESIS (2008)

Article Biochemistry & Molecular Biology

Focal Adhesion Kinase Versus p53: Apoptosis or Survival?

William G. Cance et al.

SCIENCE SIGNALING (2008)

Article Biochemistry & Molecular Biology

Cellular characterization of a novel focal adhesion kinase inhibitor

Jill K. Slack-Davis et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

N-MYC regulates focal adhesion kinase expression in human neuroblastoma

Elizabeth A. Beierle et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Crystal structure of the FERM domain of focal adhesion kinase

DFJ Ceccarelli et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Direct interaction of the N-terminal domain of focal adhesion kinase with the N-terminal transactivation domain of p53

VM Golubovskaya et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Review Pharmacology & Pharmacy

Focal adhesion kinase as a potential target in oncology

GW McLean et al.

EXPERT OPINION ON PHARMACOTHERAPY (2003)