相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Transient Low Doses of DNA-Demethylating Agents Exert Durable Antitumor Effects on Hematological and Epithelial Tumor Cells
Hsing-Chen Tsai et al.
CANCER CELL (2012)
DNA Methylation Profiling Defines Clinically Relevant Biological Subsets of Non-Small Cell Lung Cancer
Kim Walter et al.
CLINICAL CANCER RESEARCH (2012)
Aberrant global methylation patterns affect the molecular pathogenesis and prognosis of multiple myeloma
Brian A. Walker et al.
BLOOD (2011)
Epigenetic inactivation of the MIR34B/C in multiple myeloma
Kwan Yeung Wong et al.
BLOOD (2011)
MicroRNA-34a is a potent tumor suppressor molecule in vivo in neuroblastoma
Amanda Tivnan et al.
BMC CANCER (2011)
Epigenetic silencing of MIR203 in multiple myeloma
Kwan-Yeung Wong et al.
BRITISH JOURNAL OF HAEMATOLOGY (2011)
The Impact of Eliminating Socioeconomic and Racial Disparities on Premature Cancer Deaths
Rebecca Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2011)
Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer
Jung H. Kim et al.
GENOME RESEARCH (2011)
Epigenetic inactivation of the hsa-miR-203 in haematological malignancies
Chor Sang Chim et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2011)
Methylation of miR-34a, miR-34b/c, miR-124-1 and miR-203 in Ph-negative myeloproliferative neoplasms
Chor Sang Chim et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2011)
MicroRNA signatures characterize multiple myeloma patients
S. L. Corthals et al.
LEUKEMIA (2011)
Epigenetic Inactivation of the miR-124-1 in Haematological Malignancies
Kwan Yeung Wong et al.
PLOS ONE (2011)
Wild-type p53 controls cell motility and invasion by dual regulation of MET expression
Chang-Il Hwang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
DNA methylation of tumor suppressor miRNA genes: a lesson from the miR-34 family
Kwan Yeung Wong et al.
EPIGENOMICS (2011)
MicroRNAs: New Players in Multiple Myeloma
Flavia Pichiorri et al.
Frontiers in Genetics (2011)
MicroRNA-34a: A Novel Tumor Suppressor in p53-mutant Glioma Cell Line U251
Shihai Luan et al.
ARCHIVES OF MEDICAL RESEARCH (2010)
Genome-wide analysis of aberrant methylation in human breast cancer cells using methyl-DNA immunoprecipitation combined with high-throughput sequencing
Yoshinao Ruike et al.
BMC GENOMICS (2010)
Genome-wide DNA methylation profiling reveals novel epigenetically regulated genes and non-coding RNAs in human testicular cancer
H. H. Cheung et al.
BRITISH JOURNAL OF CANCER (2010)
Plasma cell leukaemia and other aggressive plasma cell malignancies
Taimur Sher et al.
BRITISH JOURNAL OF HAEMATOLOGY (2010)
被撤回的出版物: Downregulation of p53-inducible microRNAs 192, 194, and 215 Impairs the p53/MDM2 Autoregulatory Loop in Multiple Myeloma Development (Retracted article. See vol. 40, pg. 1442, 2022)
Flavia Pichiorri et al.
CANCER CELL (2010)
MicroRNA-155 Functions as an OncomiR in Breast Cancer by Targeting the Suppressor of Cytokine Signaling 1 Gene
Shuai Jiang et al.
CANCER RESEARCH (2010)
The Promise of MicroRNA Replacement Therapy
Andreas G. Bader et al.
CANCER RESEARCH (2010)
miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma
Mayuko Furuta et al.
CARCINOGENESIS (2010)
Epigenetic inactivation of the miR-34a in hematological malignancies
C. S. Chim et al.
CARCINOGENESIS (2010)
Frequent Downregulation of miR-34 Family in Human Ovarian Cancers
David C. Corney et al.
CLINICAL CANCER RESEARCH (2010)
DNA methylation profiling in cancer
Yutaka Kondo et al.
EXPERT REVIEWS IN MOLECULAR MEDICINE (2010)
Bortezomib Plus Dexamethasone Induction Improves Outcome of Patients With t(4;14) Myeloma but Not Outcome of Patients With del(17p)
Herve Avet-Loiseau et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
Methylation-mediated silencing and tumour suppressive function of hsa-miR-124 in cervical cancer
Saskia M. Wilting et al.
MOLECULAR CANCER (2010)
Deregulation of microRNA expression in the different genetic subtypes of multiple myeloma and correlation with gene expression profiling
N. C. Gutierrez et al.
LEUKEMIA (2010)
Micro-RNA-15a and micro-RNA-16 expression and chromosome 13 deletions in multiple myeloma
Sophie L. Corthals et al.
LEUKEMIA RESEARCH (2010)
Principles and challenges of genome-wide DNA methylation analysis
Peter W. Laird
NATURE REVIEWS GENETICS (2010)
High-risk myeloma is associated with global elevation of miRNAs and overexpression of EIF2C2/AGO2
Yiming Zhou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1
Ramiro Garzon et al.
BLOOD (2009)
Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial
Thorsten Zenz et al.
BLOOD (2009)
Identification of microRNA expression patterns and definition of a microRNA/mRNA regulatory network in distinct molecular groups of multiple myeloma
Marta Lionetti et al.
BLOOD (2009)
miR-34a as part of the resistance network in chronic lymphocytic leukemia
Thorsten Zenz et al.
BLOOD (2009)
MicroRNAs 15a and 16 regulate tumor proliferation in multiple myeloma
Aldo M. Roccaro et al.
BLOOD (2009)
miR-34b Targets Cyclic AMP-Responsive Element Binding Protein in Acute Myeloid Leukemia
Martina Pigazzi et al.
CANCER RESEARCH (2009)
Epigenetic Silencing of the Tumor Suppressor MicroRNA Hsa-miR-124a Regulates CDK6 Expression and Confers a Poor Prognosis in Acute Lymphoblastic Leukemia
Xabier Agirre et al.
CANCER RESEARCH (2009)
miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer
Elena Gallardo et al.
CARCINOGENESIS (2009)
Integrative High-resolution Microarray Analysis of Human Myeloma Cell Lines Reveals Deregulated miRNA Expression Associated with Allelic Imbalances and Gene Expression Profiles
Marta Lionetti et al.
GENES CHROMOSOMES & CANCER (2009)
MicroRNA 223-dependent expession of LMO2 regulates normal erythropoiesis
Nadia Felli et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2009)
MicroRNA-125b Promotes Neuronal Differentiation in Human Cells by Repressing Multiple Targets
Minh T. N. Le et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
17p13/TP53 deletion in B-CLL patients is associated with microRNA-34a downregulation
M. K. Dijkstra et al.
LEUKEMIA (2009)
Bone marrow microenvironment and the identification of new targets for myeloma therapy
K. Podar et al.
LEUKEMIA (2009)
Patterns of monoclonal gammopathy of undetermined significance and multiple myeloma in various ethnic/racial groups: support for genetic factors in pathogenesis
O. Landgren et al.
LEUKEMIA (2009)
International Myeloma Working Group molecular classification of multiple myeloma: spotlight review
R. Fonseca et al.
LEUKEMIA (2009)
miR-34a, miR-29c and miR-17-5p are downregulated in CLL patients with TP53 abnormalities
M. Mraz et al.
LEUKEMIA (2009)
Identification of a novel microRNA cluster miR-193b-365 in multiple myeloma
Kenji Unno et al.
LEUKEMIA & LYMPHOMA (2009)
MicroRNAs in chronic lymphocytic leukemia pathogenesis and disease subtypes
Marek Mraz et al.
LEUKEMIA & LYMPHOMA (2009)
Human DNA methylomes at base resolution show widespread epigenomic differences
Ryan Lister et al.
NATURE (2009)
High-resolution genome-wide cytosine methylation profiling with simultaneous copy number analysis and optimization for limited cell numbers
Mayumi Oda et al.
NUCLEIC ACIDS RESEARCH (2009)
Epigenetic alterations in cervical carcinogenesis
Anita Szalmas et al.
SEMINARS IN CANCER BIOLOGY (2009)
Current status of epigenetic treatment in myelodysplastic syndromes
Andrea Kuendgen et al.
ANNALS OF HEMATOLOGY (2008)
MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia
Ramiro Garzon et al.
BLOOD (2008)
Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres
Qing Ji et al.
BMC CANCER (2008)
miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
Joachim Silber et al.
BMC MEDICINE (2008)
Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression
Maria J. Bueno et al.
CANCER CELL (2008)
Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer
Minoru Toyota et al.
CANCER RESEARCH (2008)
Mechanisms of microRNA deregulation in human cancer
Shan Deng et al.
CELL CYCLE (2008)
Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer
Dmitri Lodygin et al.
CELL CYCLE (2008)
MicroRNAs in normal and malignant hematopoiesis
Ramiro Garzon et al.
CURRENT OPINION IN HEMATOLOGY (2008)
Breast cancer epigenetics: normal human mammary epithelial cells as a model system
Rebecca A. Hinshelwood et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2008)
Clinical and biological significance of RAS mutations in multiple myeloma
W. J. Chng et al.
LEUKEMIA (2008)
Molecular origins of cancer: Epigenetics in cancer
Manel Esteller
NEW ENGLAND JOURNAL OF MEDICINE (2008)
MicroRNAs: key players in the immune system, differentiation, tumorigenesis and cell death
R. Schickel et al.
ONCOGENE (2008)
p16INK4a Translation Suppressed by miR-24
Ashish Lal et al.
PLOS ONE (2008)
Aberrant Expression of Oncogenic and Tumor-Suppressive MicroRNAs in Cervical Cancer Is Required for Cancer Cell Growth
Xiaohong Wang et al.
PLOS ONE (2008)
MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis
Flavia Pichiorri et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Gene Hypermethylation in Multiple Myeloma: Lessons from a Cancer Pathway Approach
Chor S. Chim et al.
CLINICAL LYMPHOMA & MYELOMA (2008)
Genome-wide analysis of DNA methylation patterns
Daniel Zilberman et al.
DEVELOPMENT (2007)
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
Muller Fabbri et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth
David C. Corney et al.
CANCER RESEARCH (2007)
Methods of DNA methylation analysis
Lanlan Shen et al.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2007)
Interleukin-6-dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer
Dennis Loeffler et al.
BLOOD (2007)
p53-mediated activation of miRNA34 candidate tumor-suppressor genes
Guido T. Bommer et al.
CURRENT BIOLOGY (2007)
Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets
Teru Hideshima et al.
NATURE REVIEWS CANCER (2007)
Differential regulation of microRNAs by p53 revealed by massively parallel Sequencing -: miR-34a is a p53 target that induces apoptosis and G1-arrest
Valery Tarasov et al.
CELL CYCLE (2007)
A microRNA component of the p53 tumour suppressor network
Lin He et al.
NATURE (2007)
Clinical course and prognosis of smoldering (asymptomatic) multiple myeloma
Robert A. Kyle et al.
NEW ENGLAND JOURNAL OF MEDICINE (2007)
Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
Tsung-Cheng Chang et al.
MOLECULAR CELL (2007)
Transcriptional activation of miR-34a contributes to p53-mediated apoptosis
Nina Raver-Shapira et al.
MOLECULAR CELL (2007)
Methylation of human microRNA genes in normal and neoplastic cells
Barbara Weber et al.
CELL CYCLE (2007)
Genetic abnormalities and survival in multiple myeloma: the experience of the Intergroupe Francophone du Myelome
Herve Avet-Loiseau et al.
BLOOD (2007)
Genetic unmasking of an epigenetically silenced microRNA in human cancer cells
Amaia Lujambio et al.
CANCER RESEARCH (2007)
Molecular dissection of hyperdiploid multiple myeloma by gene expression profiling
Wee J. Chng et al.
CANCER RESEARCH (2007)
Comprehensive DNA methylation profiling in a human cancer genome identifies novel epigenetic targets
J. M. Ordway et al.
CARCINOGENESIS (2006)
Prognostic factors for hyperdiploid-myeloma:: effects of chromosome 13 deletions and IgH translocations
W Chng et al.
LEUKEMIA (2006)
Unique microRNA molecular profiles in lung cancer diagnosis and prognosis
N Yanaihara et al.
CANCER CELL (2006)
Ploidy status rarely changes in myeloma patients at disease progression
WJ Chng et al.
LEUKEMIA RESEARCH (2006)
Epigenetic therapy of cancer: past, present and future
CB Yoo et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry
M Ehrich et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
A validated FISH trisony index demonstrates the hyperdiploid and nonhyperdiploid dichotomy in MGUS
WJ Chng et al.
BLOOD (2005)
Molecular pathogenesis and a consequent classification of multiple myeloma
PL Bergsagel et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
A high-resolution map of active promoters in the human genome
TH Kim et al.
NATURE (2005)
Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma
PL Bergsagel et al.
BLOOD (2005)
Possible roles for activating RAS mutations in the MGUS to MM transition and in the intramedullary to extramedullary transition in some plasma cell tumors
T Rasmussen et al.
BLOOD (2005)
MicroRNAs: Genomics, biogenesis, mechanism, and function
DP Bartel
CELL (2004)
Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs
XZ Cai et al.
RNA (2004)
Epigenomics: Beyond CpG islands
MJ Fazzari et al.
NATURE REVIEWS GENETICS (2004)
MicroRNA genes are transcribed by RNA polymerase II
Y Lee et al.
EMBO JOURNAL (2004)
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
R Yi et al.
GENES & DEVELOPMENT (2003)
Mechanisms of disease: Gene silencing in cancer in association with promoter hypermethylation
JG Herman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
Glycosylation regulates notch signalling
N Haines et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma
R Fonseca et al.
BLOOD (2003)
The nuclear RNase III Drosha initiates microRNA processing
Y Lee et al.
NATURE (2003)
Cyclin D1 overexpression is a favorable prognostic variable for newly diagnosed multiple myeloma patients treated with high-dose chemotherapy and single or double autologous transplantation
S Soverini et al.
BLOOD (2003)
MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms
Y Zeng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Clinical and biologic implications of recurrent genomic aberrations in myeloma
R Fonseca et al.
BLOOD (2003)
Chromosome abnormalities clustering and its implications for pathogenesis and prognosis in myeloma
CS Debes-Marun et al.
LEUKEMIA (2003)
DNA methylation analysis techniques
C Dahl et al.
BIOGERONTOLOGY (2003)
Hypermethylation of gene promoters in hematological neoplasia
CS Chim et al.
HEMATOLOGICAL ONCOLOGY (2002)
MicroRNA maturation: stepwise processing and subcellular localization
Y Lee et al.
EMBO JOURNAL (2002)
Both natural and designed micro RNAs technique can inhibit the expression of cognate mRNAs when expressed in human cells
Y Zeng et al.
MOLECULAR CELL (2002)
Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentation
H Avet-Loiseau et al.
BLOOD (2002)
A long-term study of prognosis in monoclonal gammopathy of undetermined significance
RA Kyle et al.
NEW ENGLAND JOURNAL OF MEDICINE (2002)
Multiple myeloma: Evolving genetic events and host interactions
WM Kuehl et al.
NATURE REVIEWS CANCER (2002)
Rearrangements of the c-myc oncogene are present in 15% of primary human multiple myeloma tumors
H Avet-Loiseau et al.
BLOOD (2001)
Identification of novel genes coding for small expressed RNAs
M Lagos-Quintana et al.
SCIENCE (2001)
An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
NC Lau et al.
SCIENCE (2001)
An extensive class of small RNAs in Caenorhabditis elegans
RC Lee et al.
SCIENCE (2001)
Hypodiploidy is a major prognostic factor in multiple myeloma
NV Smadja et al.
BLOOD (2001)
Chromosome translocations in multiple myeloma
PL Bergsagel et al.
ONCOGENE (2001)
Cyclin D3 at 6p21 is dysregulated by recurrent chromosomal translocations to immunoglobulin loci in multiple myeloma
J Shaughnessy et al.
BLOOD (2001)
Ectopic expression of MAFB gene in human myeloma cells carrying (14;20)(q32;q11) chromosomal translocations
I Hanamura et al.
JAPANESE JOURNAL OF CANCER RESEARCH (2001)
Deletions of chromosome 13 in multiple myeloma identified by interphase FISH usually denote large deletions of the q arm or monosomy
R Fonseca et al.
LEUKEMIA (2001)
Methylation matters
JF Costello et al.
JOURNAL OF MEDICAL GENETICS (2001)
Chromosomal stability and the DNA double-stranded break connection
DC van Gent et al.
NATURE REVIEWS GENETICS (2001)
High incidence of N and K-Ras activating mutations in multiple myeloma and primary plasma cell leukemia at diagnosis
S Bezieau et al.
HUMAN MUTATION (2001)
Chromosome 13 abnormalities in multiple myeloma are mostly monosomy 13
H Avet-Loiseau et al.
BRITISH JOURNAL OF HAEMATOLOGY (2000)
MethyLight: a high-throughput assay to measure DNA methylation
Cindy A. Eads et al.
NUCLEIC ACIDS RESEARCH (2000)
DNA methylation: past, present and future directions
KD Robertson et al.
CARCINOGENESIS (2000)
Large-scale human promoter mapping using CpG islands
IP Ioshikhes et al.
NATURE GENETICS (2000)