期刊
PROTEIN AND PEPTIDE LETTERS
卷 12, 期 1, 页码 49-67出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/0929866053405959
关键词
antimicrobial; peptide; resistance; mechanism
资金
- NIAID NIH HHS [AI-48031] Funding Source: Medline
- NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [R01AI048031] Funding Source: NIH RePORTER
Antimicrobial peptides are present in organisms spanning virtually every kingdom, and employ sophisticated mechanisms to exert rapid microbicidal action consistent with their key roles in host defense. Offsetting these mechanisms, some microbial pathogens have evolved complex countermeasures to neutralize exposure to and subvert mechanisms of antimicrobial peptides. The following discussion highlights recent advances that offer greater understanding of the mechanisms of action and resistance of antimicrobial peptides.
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