期刊
MICRON
卷 36, 期 7-8, 页码 593-601出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.micron.2005.05.009
关键词
bone; collagen; electron microscopy; ultrastructure; electron-optical data; image analysis
类别
Bone collagen structure in normal and pathological tissues is illustrated using techniques of thin section transmission electron microscopy and computer-assisted analysis. The normal bone collagen types, fibril architecture and diameter are described. In pathological tissue, deviations from normal fine structure are reflected in abnormal arrangements of collagen fibrils and abnormalities in fibril diameter. Computer analyses of normal fibril positive staining patterns are presented in order to provide a basis for comparing such patterns with pathological ones. (c) 2005 Elsevier Ltd. All rights reserved.
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