期刊
CNS DRUGS
卷 19, 期 4, 页码 325-334出版社
ADIS INT LTD
DOI: 10.2165/00023210-200519040-00005
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资金
- NCRR NIH HHS [M01-RR-00071] Funding Source: Medline
- NINDS NIH HHS [K24NS02253] Funding Source: Medline
- NATIONAL CENTER FOR RESEARCH RESOURCES [M01RR000071] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [K24NS002253] Funding Source: NIH RePORTER
Peripheral neuropathy is associated with numerous systemic illnesses including HIV infection. Neuropathic pain constitutes approximately 25-50% of all pain clinic visits. Distal symmetrical polyneuropathy (DSP) is the most common form of peripheral neuropathy in individuals with HIV infection. DSP is distinguished from other forms of neuropathy on the basis of history and neurological examination. The pain associated with DSP can be debilitating. Therefore, it is important to diagnose HIV-associated DSP properly and treat the neuropathic pain in order to improve quality of life. We review the clinical manifestations, epidemiology, pathophysiology and management strategies for HIV-associated DSP.
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