NaHSO4 supported on silica gel: an alternative catalyst for Ferrier rearrangement of glycals

NaHSO4 supported on silica gel catalyses the Ferrier rearrangement reaction of 3,4,6-tri-O-acetyl-D-glucal with alcohols and thiols to give the corresponding 2,3-unsaturated glycosides in high anomeric selectivity and good to excellent yield in short reaction time. (C) 2011 Elsevier Ltd. All rights reserved.