期刊
CARBOHYDRATE RESEARCH
卷 346, 期 12, 页码 1564-1568出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.carres.2011.04.044
关键词
Propargyl glycosides; Click chemistry; Hydroxyapatite; Biomaterials; Lectin
资金
- MIUR [FIRB RBPO68JL9]
- FONDAZIONE CARIPLO [2008/3175]
An efficient method for the direct and covalent decoration of granules of nanostructured apatite with a sample monosaccharide is presented: the hydroxyapatite material was directly functionalised with a short azido-containing spacer arm, to which alpha-propargyl glucopyranoside has been chemoselectively ligated by Huisgen-type cycloaddition. The 'glycosylated' hydroxypatite was characterised by its ability to interact with glucose recognising lectins. (C) 2011 Elsevier Ltd. All rights reserved.
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