期刊
CARBOHYDRATE RESEARCH
卷 344, 期 13, 页码 1628-1631出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.carres.2009.05.022
关键词
Glycoglycerolipid; Myt1-kinase; Glycosylation
资金
- Kultusministerium des Landes Sachsen-Anhalt
The first total synthesis of 1,2-dipalmitoyl-3-(N-palmitoyl-6'-amino-6'-deoxy-alpha-D-glucosyl)-sn-glycerol, a glycoglycerolipid isolated from a marine alga extract, is described. Starting from alpha-methylglucopyranoside the multistep strategy allows the stereoselective synthesis of the final compound using various protective group procedures as well as derivatization of partial molecule domains. The latter offers the development of lead structures for inhibitors of human Myt1-kinase. (C) 2009 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据