期刊
CARBOHYDRATE RESEARCH
卷 344, 期 16, 页码 2137-2143出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.carres.2009.08.033
关键词
Carbohydrate; Drug delivery; Glycoconjugate; Lectin; Oligoribonucleotide
资金
- Research Corporation
- Natural Sciences and Engineering Research Council of Canada
- Canada Foundation for Innovation
Oligoribonucleotide (RNA)-carbohydrate conjugates bearing mono- and divalent mannosides were readily obtained using 3,4-diethoxy-3-cyclobutene-1,2-dione as the linking agent in the presence of trace amount of triethylamine. The glycoconjugates were purified by HPLC and characterized by electrospray mass spectroscopy. (C) 2009 Elsevier Ltd. All rights reserved.
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