期刊
CARBOHYDRATE RESEARCH
卷 344, 期 13, 页码 1654-1659出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.carres.2009.06.003
关键词
Synthesis; Glucosidation; Pyrazoles; N-beta-D-Glucosides; N,O-Bis(beta-D-glucosides); Antimicrobial activity
Synthesis of some novel 4-arylhydrazono-5-trifluoromethyl-2,4-dihydropyrazol-3-ones, their N- and N,O-bis- beta-D-glucosides is described. Antimicrobial evaluation of eight selected compounds against Aspergillus fumigatus RCMB 002008 (1), Penicillium italicum RCMB 001018 (1), Syncephalastrum racemosum RCMB 016001, Candida albicans RCMB 005003, Staphylococcus aureus RCMB 106-001 (1), Neudomonas aeruginosa RCMB 102-002, Bacillus subtilis RCMB 101-001, and Escherichia coli RCMB 103-001 has been achieved. The screening results indicated that all the tested compounds exhibited different inhibitory effects against five to seven different organisms of the eight test organisms. (C) 2009 Elsevier Ltd. All rights reserved.
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