Development of cellulose paper testing strips for quick measurement of glucose using chromogen agent

Cellulose paper based glucose test strips were successfully prepared using 2,4,6-tribromo-3-hydroxy benzoic acid (TBHBA) as the chromogen agent. Cellulose paper is a good substrate for carrying chromogen agents and other chemicals so that the quantitative analysis can be done based on the colorimetric chemistry. The color intensity of the developed compounds, which was measured as the differential diffusive reflectance of the test strip at 510 nm, was correlated to the glucose concentration of the sample solutions in the range of 0.18-9.91 mg/ml. These colorimetric test strips could be conveniently used, do not have to use an electronic device, and would have potential applications in the home monitoring of blood glucose for people with diabetes. (C) 2012 Elsevier Ltd. All rights reserved.